Retinoblastoma Binding Protein 8 Antikörper (pSer327)

Produktnummer ABIN8124334

Der Kaninchen Polyklonal anti-Retinoblastoma Binding Protein 8 Antikörper (ABIN8124334) detektiert spezifisch Retinoblastoma Binding Protein 8 in ELISA und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Retinoblastoma Binding Protein 8 Antikörper (pSer327) (ABIN8124334)

Target: Retinoblastoma Binding Protein 8 (RBBP8)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Retinoblastoma Binding Protein 8 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-Retinoblastoma Binding Protein 8 Antikörper

Bindungsspezifität: pSer327

Verwendungszweck: CTIP (Phospho Ser327) Antibody

Spezifität: This antibody detects endogenous levels of Human,Mouse CTIP (Phospho Ser327)

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human CTIP (Phospho Ser327)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-2000 ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Retinoblastoma Binding Protein 8

Target: Retinoblastoma Binding Protein 8 (RBBP8)

Andere Bezeichnung: CTIP

Hintergrund:

Synonyms: DNA endonuclease RBBP8 (EC 3.1.-.-, CtBP-interacting protein, CtIP, Retinoblastoma-binding protein 8, RBBP-8, Retinoblastoma-interacting protein and myosin-like, RIM, Sporulation in the absence of SPO11 protein 2 homolog, SAE2)

Background: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008],

Gene Name: RBBP8 CTIP

Protein Name: CTIP (Phospho Ser327)

Gen-ID: 5932

UniProt: Q99708

Pathways: Zellzyklus, DNA Reparatur