PDK4 Antikörper (AA 34-84)
Kurzübersicht für PDK4 Antikörper (AA 34-84) (ABIN8124179)
Target
Alle PDK4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 34-84
-
Verwendungszweck
- PDK4 Antibody
-
Spezifität
- This antibody detects endogenous levels of PDK4 at Human, Mouse,Rat
-
Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogen
- Synthesized peptide derived from human PDK4 AA range: 34-84
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- IHC1:50-200 ,WB 1:1000-2000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C/1 year
-
Haltbarkeit
- 12 months
-
-
- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
-
Andere Bezeichnung
- PDK4
-
Hintergrund
-
Synonyms: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4)
Background: Pyruvate dehydrogenase kinase isoform4 (PDK4) is also named as PDHK4 and belongs to the PDK/BCKDK protein kinase family. It is upregulated by starvation in many tissues of the body during starvation. This causes inactivation of the pyruvate dehydrogenase complex which blocks pyruvate oxidation and conserves lactate and alanine for gluconeogenesis.
Gene Name: PDK4 PDHK4
Protein Name: PDK4
-
Gen-ID
- 5166
-
UniProt
- Q16654
-
Pathways
- PI3K-Akt Signalweg, Hedgehog Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
Target
-