NAIP Antikörper (AA 1191-1240)

Produktnummer ABIN8123355

Der Kaninchen Polyklonal anti-NAIP Antikörper wird verwendet zum Nachweis von NAIP in Proben von Human und Maus. Er wurde validiert für IHC, ELISA und IF.

Kurzübersicht für NAIP Antikörper (AA 1191-1240) (ABIN8123355)

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAIP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-NAIP Antikörper

Bindungsspezifität: AA 1191-1240

Verwendungszweck: NAIP Antibody

Spezifität: The antibody detects endogenous NAIP

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 1191-1240

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu NAIP

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Andere Bezeichnung: NAIP

Hintergrund:

Synonyms: Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)

Background: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length, additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1.The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by Ref

Gene Name: NAIP BIRC1

Protein Name: Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)

Gen-ID: 4671

UniProt: Q13075

Pathways: Apoptose, Inflammasome