MAPK11 Antikörper (N-Term)

Produktnummer ABIN8105615

Der Kaninchen Polyklonal anti-MAPK11 Antikörper wird verwendet zum Nachweis von MAPK11 in Proben von Human, Maus, Ratte, Rind (Kuh) und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für MAPK11 Antikörper (N-Term) (ABIN8105615)

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAPK11 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MAPK11 Antibody - N-terminal region

Sequenz: MSGPRAGFYR QELNKTVWEV PQRLQGLRPV GSGAYGSVCS AYDARLRQKV

Homologie: Cow: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 91%

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MK11

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56437-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MAPK11

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Andere Bezeichnung: MAPK11

Hintergrund:

Background Information: This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants.

Gene Name: mitogen-activated protein kinase 11

Alternative Symbols: P38B, SAPK2, p38-2, PRKM11, SAPK2B, p38Beta, P38BETA2

Protein Name: mitogen-activated protein kinase 11

Molekulargewicht: 40kDa

Gen-ID: 5600

NCBI Accession: NP_002742

UniProt: Q15759

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteine