ELK1 Antikörper (pThr417) (Biotin)

Produktnummer ABIN758334

Dieses Anti-ELK1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ELK1 in WB, ELISA, IHC (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für ELK1 Antikörper (pThr417) (Biotin) (ABIN758334)

Target: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELK1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ELK1 Antikörper (Biotin)

Bindungsspezifität: pThr417

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human ELk1 around the phosphorylation site of Thr417 [LS(p-T)PV]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu ELK1

Target: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Andere Bezeichnung: ELk1

Hintergrund:

Synonyms: ELK1 phospho T417, Elk-1Thr417, p-ELK1 T417, p-Elk-1Thr417, ELK 1, ELK1 member of ETS oncogene family, ELK1 protein, ELK2 member of ETS oncogene family, ETS domain containing protein Elk 1, ETS domain containing protein Elk1, ETS domain protein Elk1, Oncogene Elk1, ETS domain-containing protein Elk-1 isoform a, ETS domain-containing protein Elk-1, ETS-like gene 1, tyrosine kinase ELK1 oncogene, ELK1_HUMAN.

Background: This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012].

Gen-ID: 2002

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling