GIP Antikörper

Produktnummer ABIN8065467

Der Maus Monoklonal anti-GIP Antikörper wird verwendet zum Nachweis von GIP in Proben von Human. Er wurde validiert für IHC und ELISA.

Kurzübersicht für GIP Antikörper (ABIN8065467)

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GIP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Güteklasse: Carrier-free

Klon: 4

Produktdetails anti-GIP Antikörper

Verwendungszweck: Anti-Gastric Inhibitory Polypeptide Antibody

Spezifität: ABIN8065467 binds human GIP. ABIN8065467 cross-reacts up to 10 % with PACAP and human GLP-2 but <0.1 % with glucagon, GLP-1 or VIP.

Homologie: Human

Aufreinigung: Protein A or Protein G purified

Immunogen: Synthetic human gastric inhibitory polypeptide

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C without exposure to light

Haltbarkeit: 24 months

Details zu GIP

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Andere Bezeichnung: Gastric Inhibitory Polypeptide

Hintergrund: GIP, gastric inhibitory polypeptide, glucose-dependent insulinotropic polypeptide, incretin hormone,Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.,GIP,Human gastric inhibitory polypeptide (GIP) is a 42 amino acid peptide belonging to the glucagon-secretin family of peptide hormones. It is secreted by endocrine cells in the duodenal mucosa and stimulates glucose-dependent insulin secretion as well as GLP-1 release from more distal endocrine (L) cells in the intestinal mucosa. GIP shows amino-acid sequence similarities to glucagon, GLP-1 and GLP-2 (from approximately 50 % identity for glucagon to 30 % identity for GLP-2).

Molekulargewicht: 17 kDa

Gen-ID: 2695

UniProt: P09681

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism