WWTR1 Antikörper (AA 1-396)
Kurzübersicht für WWTR1 Antikörper (AA 1-396) (ABIN8054568)
Target
Alle WWTR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- AA 1-396
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Verwendungszweck
- Anti-WWTR1 Antibody
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Produktmerkmale
- Anti-WWTR1 Antibody. Tested in WB, IHC, ICC/IF, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human WWTR1 recombinant protein (Position: M1-F396).
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Isotyp
- IgG
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Applikationshinweise
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing. -
Haltbarkeit
- 12 months
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- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
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Andere Bezeichnung
- WWTR1
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Hintergrund
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Background: WW domain-containing transcription regulator protein 1 (WWTR1), also known as Transcriptional coactivator with PDZ-binding motif (TAZ), is a protein that in humans is encoded by the WWTR1 gene. WWTR1 acts as a transcriptional coregulator and has no effect on transcription alone. When in complex with transcription factor binding partners, WWTR1 helps promote gene expression in pathways associated with development, cell growth and survival, and inhibiting apoptosis. Aberrant WWTR1 function has been implicated for its role in driving cancers. WWTR1 is often referred to as TAZ due to its initial characterization with the name TAZ. However, WWTR1 (TAZ) is not to be confused with the protein tafazzin, which originally held the official gene symbol TAZ, and is now TAFAZZIN.
Gene Full Name: WW domain containing transcription regulator 1
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Molekulargewicht
- 50 kDa
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Gen-ID
- 25937
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UniProt
- Q9GZV5
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Target
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