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WWTR1 Antikörper (N-Term)

WWTR1 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779708
  • Target Alle WWTR1 Antikörper anzeigen
    WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
    Bindungsspezifität
    • 11
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen
    Wirt
    • 33
    • 4
    Kaninchen
    Klonalität
    • 33
    • 4
    Polyklonal
    Konjugat
    • 22
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser WWTR1 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 16
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    PRLAGGAQHV RSHSSPASLQ LGTGAGAAGS PAQQHAHLRQ QSYDVTDELP
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against WWTR1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human WWTR1
    Top Product
    Discover our top product WWTR1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 400 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
    Andere Bezeichnung
    WWTR1 (WWTR1 Produkte)
    Synonyme
    WWTR1 antikoerper, TAZ antikoerper, 2310058J06Rik antikoerper, 2610021I22Rik antikoerper, C78399 antikoerper, Taz antikoerper, WW domain containing transcription regulator 1 L homeolog antikoerper, WW domain containing transcription regulator 1 antikoerper, wwtr1.L antikoerper, wwtr1 antikoerper, WWTR1 antikoerper, Wwtr1 antikoerper
    Hintergrund
    TAZ (transctiptional coactivator with PDZ-binding motif), also known as WW domain containing transcription regulator 1 (WWTR1), is a member of the bicoid sub-family of homeodomain-containing transcription factors. TAZ is a 14-3-3 binding protein that co-activates Runx2-dependent gene transcription while repressing PPAR-gamma-dependent gene transcription. TAZ has been reported to be a modulator of mesenchymal stem cell differentiation. TAZ may also play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.
    Alias Symbols: DKFZP586I1419, TAZ
    Protein Interaction Partner: MED28, NOTCH1, YWHAQ, LATS1, BTRC, YWHAE, TP53BP2, PPP1CA, KLF5, YWHAZ, YWHAG, PAX3, SLC9A3R2, TEAD3, TEAD4, NKX2-1, RUNX1,
    Protein Size: 400
    Molekulargewicht
    44 kDa
    Gen-ID
    25937
    NCBI Accession
    NM_015472, NP_056287
    UniProt
    Q9GZV5
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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