SOS1 Antikörper (AA 177-1288)

Produktnummer ABIN8040809

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SOS1 in WB, ELISA, IHC und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SOS1 Antikörper (AA 177-1288) (ABIN8040809)

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Produktdetails anti-SOS1 Antikörper

Bindungsspezifität: AA 177-1288

Verwendungszweck: Anti-SOS1 Antibody

Homologie: Human SOS1 shares 96.5% amino acid (aa) sequence identity with mouse SOS1.

Produktmerkmale: Anti-SOS1 Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SOS1 recombinant protein (Position: H177-A1288). Human SOS1 shares 96.5% amino acid (aa) sequence identity with mouse SOS1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SOS1

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Andere Bezeichnung: SOS1

Hintergrund:

Background: Son of sevenless homolog 1 is a protein that in humans is encoded by the SOS1 gene. This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.

Gene Full Name: SOS Ras/Rac guanine nucleotide exchange factor 1

Molekulargewicht: 170 kDa

Gen-ID: 6654

UniProt: Q07889

Pathways: RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling