SOS1 Antikörper (AA 1140-1281)

Produktnummer ABIN7170318

Der Kaninchen Polyklonal anti-SOS1 Antikörper wird verwendet zum Nachweis von SOS1 in Proben von Human. Er wurde validiert für WB, ELISA, IF und IHC.

Kurzübersicht für SOS1 Antikörper (AA 1140-1281) (ABIN7170318)

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-SOS1 Antikörper

Bindungsspezifität: AA 1140-1281

Verwendungszweck: SOS1 Antibody

Kreuzreaktivität: Ratte

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Human Son of sevenless homolog 1 protein (1140-1281AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SOS1

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Andere Bezeichnung: SOS1

Hintergrund:

Background: Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity).

Aliases: alternate SOS1 antibody, GF1 antibody, GGF1 antibody, GINGF antibody, gingival fibromatosis antibody, gingival fibromatosis hereditary 1 antibody, Guanine nucleotide exchange factor antibody, HGF antibody, NS4 antibody, Son of sevenless homolog 1 (Drosophila) antibody, Son of sevenless homolog 1 antibody, SOS Ras/Rac guanine nucleotide exchange factor 1 antibody, SOS-1 antibody, Sos1 antibody, SOS1_HUMAN antibody

UniProt: Q07889

Pathways: RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling