Retinoblastoma Binding Protein 8 Antikörper (AA 307-702)

Produktnummer ABIN8031829

Der Kaninchen Polyklonal anti-Retinoblastoma Binding Protein 8 Antikörper (ABIN8031829) detektiert spezifisch Retinoblastoma Binding Protein 8 in ELISA, WB, IHC, IF, FACS und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Retinoblastoma Binding Protein 8 Antikörper (AA 307-702) (ABIN8031829)

Target: Retinoblastoma Binding Protein 8 (RBBP8)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Retinoblastoma Binding Protein 8 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Güteklasse: Carrier-free

Produktdetails anti-Retinoblastoma Binding Protein 8 Antikörper

Bindungsspezifität: AA 307-702

Verwendungszweck: Anti-RBBP8 Antibody

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human RBBP8 shares 68.9%,66.7% amino acid (aa) sequence identity with mouse,rat RBBP8,respectively.

Produktmerkmale: Anti-RBBP8 Antibody. Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RBBP8 recombinant protein (Position: R307-K702). Human RBBP8 shares 68.9% and 66.7% amino acid (aa) sequence identity with mouse and rat RBBP8, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Retinoblastoma Binding Protein 8

Target: Retinoblastoma Binding Protein 8 (RBBP8)

Andere Bezeichnung: RBBP8

Hintergrund:

Background: Retinoblastoma-binding protein 8 is a protein that in humans is encoded by the RBBP8 gene. The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind ly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.

Gene Full Name: RB binding protein 8, endonuclease

Molekulargewicht: 130 kDa

Gen-ID: 5932

UniProt: Q99708

Pathways: Zellzyklus, DNA Reparatur