KDM5B Antikörper (Middle Region) (Fluoro594)

Produktnummer ABIN8006970

Der Kaninchen Polyklonal anti-KDM5B Antikörper wird verwendet zum Nachweis von KDM5B in Proben von Human, Maus, Ratte und Affe. Er wurde validiert für FACS.

Kurzübersicht für KDM5B Antikörper (Middle Region) (Fluoro594) (ABIN8006970)

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM5B Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-KDM5B Antikörper (Fluoro594)

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-KDM5B/PLU1/Jarid1B Antibody Fluoro594 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse,rat sequences.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human KDM5B, identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu KDM5B

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Andere Bezeichnung: KDM5B

Hintergrund:

Background: Lysine-specific demethylase 5B, also known as histone demethylase JARID1B, is a demethylase enzyme that in humans is encoded by the KDM5B gene. This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing resultsi n multiple transcript variants.

Gene Full Name: lysine demethylase 5B

Gen-ID: 10765

UniProt: Q9UGL1

Pathways: Warburg Effekt