KDM5B Antikörper (AA 231-319)
Kurzübersicht für KDM5B Antikörper (AA 231-319) (ABIN1327126)
Target
Alle KDM5B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 231-319
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Verwendungszweck
- Mouse monoclonal antibody raised against a partial recombinant KDM5B.
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Sequenz
- AKRMRAEAMN IKIEPEETTE ARTHNLRRRM GCPTPKCENE KEMKSSIKQE PIERKDYIVE NEKEKPKSRS KKATNAVDLY VCLLCGSGN
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Antibody Reactive Against Recombinant Protein.
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Immunogen
- KDM5B (NP_006609, 231 a.a. ~ 319 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Isotyp
- IgG2a
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1x PBS, pH 7.4
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Handhabung
- Aliquot to avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "Jumonji/ARID1 B (JARID1B) protein promotes breast tumor cell cycle progression through epigenetic repression of microRNA let-7e." in: The Journal of biological chemistry, Vol. 286, Issue 47, pp. 40531-5, (2011) (PubMed).
: "Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway." in: Molecular cancer, Vol. 9, pp. 59, (2010) (PubMed).
: "JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 49, pp. 19226-31, (2007) (PubMed).
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- KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
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Andere Bezeichnung
- KDM5B
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Hintergrund
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Full Gene Name: jumonji, AT rich interactive domain 1B
Synonyms: FLJ10538,FLJ12459,FLJ12491,FLJ16281,FLJ23670,KDM5B,PLU-1,PUT1,RBBP2H1A -
Gen-ID
- 10765
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NCBI Accession
- NM_006618
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Pathways
- Warburg Effekt
Target
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