KDM5B Antikörper (AA 1494-1544)
Kurzübersicht für KDM5B Antikörper (AA 1494-1544) (ABIN7448613)
Target
Alle KDM5B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1494-1544
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Verwendungszweck
- Rabbit anti-JARID1B IHC Antibody, Affinity Purified
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Homologie
- Mouse,Dog,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Small-eared galago,Northern white-cheeked gibbon,White-tufted-ear marmoset,African elephant
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 1494 and 1544
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Isotyp
- IgG
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Applikationshinweise
- 1:100 - 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 250 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
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Andere Bezeichnung
- JARID1B
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Hintergrund
- Background: JARID1B (Jumonji AT-rich interactive domain 1B) is a member of the JARID 1 family of proteins that catalyze the demethylation of histones on lysine. The Jarid 1 family members include JARID1A, JARID1B, JARID1C and JARID1D. The members of this family possess a Jumonji C (JmjC) and Jumonji N (JmjN) domain as well as one ARID (AT-rich interactive domain) and three PHD-type zinc fingers. As histone demethylases, JARID 1 proteins function as transcriptional repressors. JARID1B expression is largely restricted to testis and may play a critical role in tumorigenesis as it has been found to be upregulated in prostate and breast cancer.
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Gen-ID
- 10765
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NCBI Accession
- NP_006609
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UniProt
- Q9UGL1
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Pathways
- Warburg Effekt
Target
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