GZMB Antikörper (AA 21-247) (HRP)

Produktnummer ABIN7995048

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GZMB in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für GZMB Antikörper (AA 21-247) (HRP) (ABIN7995048)

Target: GZMB (Granzyme B (GZMB))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GZMB Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-GZMB Antikörper (HRP)

Bindungsspezifität: AA 21-247

Verwendungszweck: Anti-Granzyme B/Gzmb Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse Granzyme B recombinant protein (Position: I21-S247).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GZMB

Target: GZMB (Granzyme B (GZMB))

Andere Bezeichnung: Gzmb

Hintergrund:

Background: Granzyme B is a serine protease that in humans is encoded by the GZMB gene. Granzyme B is expressed by cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. CTL and NK cells share the remarkable ability to recognize specific infected target cells. They are thought to protect their host by inducing apoptosis of cells that bear on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

Gene Full Name: granzyme B

Gen-ID: 14939

UniProt: P04187

Pathways: Apoptose, Caspase Kaskade in der Apoptose