Crossover junction endonuclease EME1 (EME1) (C-Term) Antikörper (Fluoro594)

Produktnummer ABIN7981848

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Crossover junction endonuclease EME1 in FACS. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für Crossover junction endonuclease EME1 (EME1) (C-Term) Antikörper (Fluoro594) (ABIN7981848)

Target: Crossover junction endonuclease EME1 (EME1)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails

Bindungsspezifität: C-Term

Verwendungszweck: Anti-EME1 Antibody Fluoro594 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by five amino acids.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human EME1, different from the related mouse sequence by five amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Antigendetails

Target: Crossover junction endonuclease EME1 (EME1)

Andere Bezeichnung: EME1

Hintergrund:

Background: Crossover junction endonuclease EME1 is an enzyme that in humans is encoded by the EME1 gene. It is mapped to 17q21.33. This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. Also, this protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.

Gene Full Name: essential meiotic structure-specific endonuclease 1

Gen-ID: 146956

UniProt: Q96AY2