Crossover junction endonuclease EME1 (EME1) (AA 250-330) Antikörper

Produktnummer ABIN7219782

Der Kaninchen Polyklonal anti-Crossover junction endonuclease EME1 Antikörper wird verwendet zum Nachweis von Crossover junction endonuclease EME1 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Crossover junction endonuclease EME1 (EME1) (AA 250-330) Antikörper (ABIN7219782)

Target: Crossover junction endonuclease EME1 (EME1)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails

Bindungsspezifität: AA 250-330

Verwendungszweck: Rabbit Anti-Eme1 Polyclonal Antibody

Spezifität: Eme1 Polyclonal Antibody detects endogenous levels of Eme1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Eme1 at AA range: 250-330

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: Crossover junction endonuclease EME1 (EME1)

Andere Bezeichnung: Eme1

Hintergrund: EME1, MMS4, Crossover junction endonuclease EME1, MMS4 homolog, hMMS4EME1 encodes essential meiotic structure-specific endonuclease 1 that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 65kD

Gen-ID: 146956

UniProt: Q96AY2