CHEK1 Antikörper (AA 1-210) (Fluoro488)
Kurzübersicht für CHEK1 Antikörper (AA 1-210) (Fluoro488) (ABIN7978345)
Target
Alle CHEK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-210
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Verwendungszweck
- Anti-Chk1/CHEK1 Antibody Fluoro488 Conjugated
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Spezifität
- No cross reactivity with other proteins.
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Homologie
- Human Chk1 shares 96.7%,97.6% amino acid (aa) sequence identity with mouse,rat Chk1,respectively.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human Chk1 recombinant protein (Position: M1-Q210). Human Chk1 shares 96.7% and 97.6% amino acid (aa) sequence identity with mouse and rat Chk1, respectively.
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Isotyp
- IgG
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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Andere Bezeichnung
- CHEK1
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Hintergrund
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Background: CHEK1, Cell cycle checkpoint kinase, is an enzyme that in humans is encoded by the CHEK1 gene. By fluorescence in situ hybridization, the human CHEK1 gene is mapped to 11q24, near the ATM gene at 11q23. CHEK1 is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Furthermore, CHEK1 acts to integrate signals from ATM and ATR, and is involved in monitoring meiotic recombination, a process that involves programmed DNA breaks.
Gene Full Name: checkpoint kinase 1
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Gen-ID
- 1111
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UniProt
- O14757
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Pathways
- p53 Signalweg, Apoptose, Zellzyklus, DNA Reparatur
Target
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