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CHEK1 Antikörper (AA 1-210) (Biotin)

Der Biotin-konjugierte Kaninchen Polyklonal anti-CHEK1 Antikörper (ABIN7978343) detektiert spezifisch CHEK1 in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Produktnummer ABIN7978343
720,50 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 8 bis 12 Werktagen

Kurzübersicht für CHEK1 Antikörper (AA 1-210) (Biotin) (ABIN7978343)

Target

Alle CHEK1 Antikörper anzeigen
CHEK1 (Checkpoint Kinase 1 (CHEK1))

Reaktivität

  • 240
  • 133
  • 83
  • 16
  • 11
  • 8
  • 6
  • 6
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Human

Wirt

  • 251
  • 15
  • 5
  • 3
Kaninchen

Klonalität

  • 202
  • 73
Polyklonal

Konjugat

  • 136
  • 15
  • 10
  • 9
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Dieser CHEK1 Antikörper ist konjugiert mit Biotin

Applikation

  • 216
  • 87
  • 77
  • 71
  • 54
  • 41
  • 40
  • 30
  • 24
  • 21
  • 10
  • 7
  • 6
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 38
    • 31
    • 20
    • 20
    • 18
    • 11
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-210

    Verwendungszweck

    Anti-Chk1/CHEK1 Antibody Biotin Conjugated

    Spezifität

    No cross reactivity with other proteins.

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Homologie

    Human Chk1 shares 96.7%,97.6% amino acid (aa) sequence identity with mouse,rat Chk1,respectively.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Chk1 recombinant protein (Position: M1-Q210). Human Chk1 shares 96.7% and 97.6% amino acid (aa) sequence identity with mouse and rat Chk1, respectively.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    Haltbarkeit

    12 months
  • Target

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    Andere Bezeichnung

    CHEK1

    Hintergrund

    Background: CHEK1, Cell cycle checkpoint kinase, is an enzyme that in humans is encoded by the CHEK1 gene. By fluorescence in situ hybridization, the human CHEK1 gene is mapped to 11q24, near the ATM gene at 11q23. CHEK1 is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Furthermore, CHEK1 acts to integrate signals from ATM and ATR, and is involved in monitoring meiotic recombination, a process that involves programmed DNA breaks.

    Gene Full Name: checkpoint kinase 1

    Gen-ID

    1111

    UniProt

    O14757

    Pathways

    p53 Signalweg, Apoptose, Zellzyklus, DNA Reparatur
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