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IL1R1 Antikörper (AA 481-569)

Name: IL1R1 Antikörper (AA 481-569)
SKU: ABIN747743
Price: 384.62 EUR
Availability: InStock

IL1R1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat colitis tissue labeled with Anti-IL-1R1 CD121a IL1 Receptor I Polyclonal Antibody, unconjugated (ABIN747743) at 1:200 followed by incubation with conjugated secondary antibody and DAB staining (IL1R1 Antikörper (AA 481-569))

IHC

Formalin-fixed and paraffin embedded rat colitis labeled with Anti-IL-1R1/CD121a/IL1 Receptor I Polyclonal Antibody, Unconjugated (ABIN747743) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (IL1R1 Antikörper (AA 481-569))

SDS

L1 rat brain lysates L2 rat kidney lysates probed with Anti IL-1R1/CD121a/IL1 Receptor I Polyclonal Antibody, Unconjugated (ABIN747743) at 1:200 overnight at 4 °C. (IL1R1 Antikörper (AA 481-569))

IHC

Formalin-fixed and paraffin embedded rat colitis labeled with Anti-IL-1R1/CD121a/IL1 Receptor I Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (IL1R1 Antikörper (AA 481-569))

IHC (p)

Paraformaldehyde-fixed, paraffin embedded rat spleen, Antigen retrieval by boiling in sodium citrate buffer (pH6. (IL1R1 Antikörper (AA 481-569))

IHC (p)

5 Abbildungen

Produktnummer ABIN747743

Datenblatt (PDF)

Target Alle IL1R1 Antikörper anzeigen

IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
Bindungsspezifität
25

15

8

8

8

7

7

4

4

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 481-569
Reaktivität
113

64

47

5

3

2

2

1

1

1

1
Human, Maus, Ratte
Wirt
104

15

11

5

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
110

28
Polyklonal
Konjugat
65

13

9

6

6

6

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser IL1R1 Antikörper ist unkonjugiert
Applikation
110

56

46

34

18

14

13

13

10

8

6

5

4

3

2

2

2

2

1

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität

Human, Maus, Ratte

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human IL-1R1

Isotyp

IgG

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IL1R1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Target

IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Andere Bezeichnung

IL-1R1 (IL1R1 Produkte)

Hintergrund

Synonyms: P80, IL1R, IL1RA, CD121A, D2S1473, IL-1R-alpha, Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, Interleukin-1 receptor type I, IL1R1, IL1RT1
Background: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.

Gen-ID

3554

UniProt

P14778

Pathways

NF-kappaB Signalweg, Carbohydrate Homeostasis, Cancer Immune Checkpoints