Survivin Antikörper (AA 1-140) (FITC)

Produktnummer ABIN7972016

Der FITC-konjugierte Kaninchen Polyklonal anti-Survivin Antikörper (ABIN7972016) detektiert spezifisch Survivin in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für Survivin Antikörper (AA 1-140) (FITC) (ABIN7972016)

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Survivin Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Survivin Antikörper (FITC)

Bindungsspezifität: AA 1-140

Verwendungszweck: Anti-Survivin/BIRC5 Antibody FITC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Mouse Survivin shares 85%,91% amino acid (aa) sequence identity with human,rat Survivin,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Survivin recombinant protein (Position: M1-A140). Mouse Survivin shares 85% and 91% amino acid (aa) sequence identity with human and rat Survivin, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Andere Bezeichnung: BIRC5

Hintergrund:

Background: Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that in humans encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin gene contains 4 exons. This gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and 2-color FISH. The survivin protein functions as inhibitor caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. The survivin protein is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.

Gene Full Name: baculoviral IAP repeat-containing 5

Sequence Similarities: Belongs to the IAP family.

Gen-ID: 11799

UniProt: O70201

Pathways: Apoptose, Zellzyklus, Nuclear Hormone Receptor Binding