Tyrosinase-Related Protein 1 Antikörper

Produktnummer ABIN7882609

Der Kaninchen Polyklonal anti-Tyrosinase-Related Protein 1 Antikörper wird verwendet zum Nachweis von Tyrosinase-Related Protein 1 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Tyrosinase-Related Protein 1 Antikörper (ABIN7882609)

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tyrosinase-Related Protein 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Tyrosinase-Related Protein 1 Antikörper

Verwendungszweck: Tyrosinase-Related Protein-1 Antibody / TRP1 / TYRP1

Aufreinigung: Protein A affinity

Immunogen: Recombinant human TYRP1 protein was used as the immunogen for the Tyrosinase-Related Protein-1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Tyrosinase-Related Protein-1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Tyrosinase-Related Protein-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Andere Bezeichnung: Tyrosinase-Related Protein-1

Hintergrund: It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

UniProt: P17643