Stathmin 1 Antikörper
Kurzübersicht für Stathmin 1 Antikörper (ABIN7882366)
Target
Alle Stathmin 1 (STMN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Oncoprotein 18 Antibody / OP18 / Stathmin 1
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A recombinant fragment of human Stathmin 1 protein was used as the immunogen for the Oncoprotein 18 antibody.
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal dilution of the Oncoprotein 18 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Oncoprotein 18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Stathmin 1 (STMN1)
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Andere Bezeichnung
- Oncoprotein 18
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Hintergrund
- Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation.Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.
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UniProt
- P16949
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Pathways
- MAPK Signalweg, Microtubule Dynamics
Target
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