Stathmin 1 Antikörper (C-Term)

Produktnummer ABIN185573

Produktdetails anti-Stathmin 1 Antikörper

Target: Stathmin 1 (STMN1)

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Stathmin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Enzyme Immunoassay (EIA)

Verwendungszweck: STMN1 / Stathmin 1

Sequenz: KNKESKDPAD ETEAD

Spezifität: This antibody is expected to cross-react with isoform 1 a (NP_005554.1, NP_981944.1, NP_981946.1) only. The three reported isoforms (NP_005554.1, NP_981944.1 and NP_981946.1) represent identical protein.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Güteklasse: Verified

Immunogen: Peptide with sequence C-KNKESKDPADETEAD, from the C Terminus of the protein sequence according to NP_005554.1, NP_981944.1, NP_981946.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: Paraffin embedded Human Thymus and Tonsil. Recommended concentration: 3.75 μg/mL.

Western Blot: Approx 17 kDa band observed in Human Testis and Mouse Brain lysates (calculated MW of 17.3 kDa according to NP_005554.1, NP_981944.1 and NP_981946.1). Recommended concentration: 1-3 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:1000.

Kommentare:

ELISA: This antibody has been successfully used in ELISA as described in the following paper: Song et al, Aging Cell. 2010 Aug,9(4):607-15, PMID: 20560902.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Referenzen für anti-Stathmin 1 Antikörper (ABIN185573)

Watabe-Rudolph, Song, Lausser, Schnack, Begus-Nahrmann, Scheithauer, Rettinger, Otto, Tumani, Thal, Attems, Jellinger, Kestler, von Arnim, Rudolph: "Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease." in: Neurology, Vol. 78, Issue 8, pp. 569-77, (2012) (PubMed).

Song, von Figura, Liu, Kraus, Torrice, Dillon, Rudolph-Watabe, Ju, Kestler, Sanoff, Lenhard Rudolph: "Lifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human blood." in: Aging cell, Vol. 9, Issue 4, pp. 607-15, (2010) (PubMed).

Details zu Stathmin 1

Target: Stathmin 1 (STMN1)

Andere Bezeichnung: STMN1 (STMN1 Produkte)

Synonyme: C1orf215 antikoerper, LAP18 antikoerper, Lag antikoerper, OP18 antikoerper, PP17 antikoerper, PP19 antikoerper, PR22 antikoerper, SMN antikoerper, 19k antikoerper, Lap18 antikoerper, Op18 antikoerper, P18 antikoerper, P19 antikoerper, Pig antikoerper, Pp17 antikoerper, Pp18 antikoerper, Pp19 antikoerper, Pr22 antikoerper, Smn antikoerper, prosolin antikoerper, op18 antikoerper, stathmin antikoerper, stmn1 antikoerper, stmn1a antikoerper, lag antikoerper, lap18 antikoerper, pp17 antikoerper, pp19 antikoerper, pr22 antikoerper, smn antikoerper, fj43c10 antikoerper, wu:fj38b07 antikoerper, wu:fj43c10 antikoerper, zgc:110159 antikoerper, cb959 antikoerper, wu:fb14e04 antikoerper, zgc:136942 antikoerper, stmn1-a antikoerper, stmn1b antikoerper, xo35 antikoerper, stathmin 1 antikoerper, stathmin 1 S homeolog antikoerper, stathmin 1b antikoerper, stathmin 1a antikoerper, stathmin-like antikoerper, stathmin antikoerper, stathmin 1 L homeolog antikoerper, STMN1 antikoerper, Stmn1 antikoerper, stmn1.S antikoerper, stmn1 antikoerper, stmn1b antikoerper, stmn1a antikoerper, LOC100229194 antikoerper, stmn1.L antikoerper

Hintergrund: STMN1, stathmin 1/oncoprotein 18 , LAP18, Lag, OP18, PP17, PP19, PR22, SMN , Pr22 protein, leukemia-associated phosphoprotein p18, metablastin, oncoprotein 18, phosphoprotein 19, prosolin, stathmin 1, stathmin 1 variant

Gen-ID: 3925

NCBI Accession: NP_005554, NP_981944, NP_981946

Pathways: MAPK Signalweg, Microtubule Dynamics