GZMB Antikörper
Kurzübersicht für GZMB Antikörper (ABIN7880924)
Target
Alle GZMB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Granzyme B Antibody
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Aufreinigung
- Affinity purified
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Immunogen
- A synthetic peptide specific to human Granzyme B / GZMB was used as the immunogen for the Granzyme B antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the Granzyme B antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the Granzyme B antibody at -20oC.
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- GZMB (Granzyme B (GZMB))
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Andere Bezeichnung
- Granzyme B
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Hintergrund
- This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
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UniProt
- P10144
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose
Target
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