Calnexin Antikörper
Kurzübersicht für Calnexin Antikörper (ABIN7880142)
Target
Alle Calnexin (CANX) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Calnexin Antibody
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- A partial human recombinant protein was used as the immunogen for the Calnexin antibody.
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- The stated application concentrations are suggested starting points. Titration of the Calnexin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the Calnexin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Calnexin (CANX)
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Andere Bezeichnung
- Calnexin
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Hintergrund
- Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse. [UniProt]
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UniProt
- P27824
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Pathways
- MAPK Signalweg, Thyroid Hormone Synthesis
Target
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