Tyrosinase-Related Protein 1 Antikörper (full length)
Kurzübersicht für Tyrosinase-Related Protein 1 Antikörper (full length) (ABIN7879273)
Target
Alle Tyrosinase-Related Protein 1 (TYRP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- full length
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Verwendungszweck
- TRP1 Antibody Cocktail / Tyrosinase-Related Protein-1 / TYRP1
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Aufreinigung
- Protein A/G affinity
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Immunogen
- SK-MEL-23 cells (clone TA99) and recombinant full-length human TYRP1 protein (clone TYRP1/807) were used as the immunogen for the TRP1 antibody cocktail.
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- Optimal dilution of the TRP1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the TRP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Tyrosinase-Related Protein 1 (TYRP1)
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Andere Bezeichnung
- TRP1
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Hintergrund
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
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UniProt
- P17643
Target
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