IRF9 Antikörper (full length)
Kurzübersicht für IRF9 Antikörper (full length) (ABIN7878453)
Target
Alle IRF9 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- full length
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Verwendungszweck
- IRF9 Antibody / Interferon regulatory factor 9
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Aufreinigung
- Protein A/G affinity
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Immunogen
- Recombinant full-length human IRF9 protein was used as the immunogen for the IRF9 antibody.
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Isotyp
- IgG2a
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Applikationshinweise
- Optimal dilution of the IRF9 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the IRF9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IRF9 (Interferon Regulatory Factor 9 (IRF9))
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Andere Bezeichnung
- IRF9
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Hintergrund
- Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
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UniProt
- Q00978
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Pathways
- JAK-STAT Signalweg, Interferon-gamma Pathway, Hepatitis C
Target
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