Der Maus Monoklonal anti-Growth Hormone 1 Antikörper wird verwendet zum Nachweis von Growth Hormone 1 in Proben von Human. Er wurde validiert für IHC (p).
Optimal dilution of the Growth Hormone antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store the Growth Hormone antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
Growth Hormone 1 (GH1)
Andere Bezeichnung
Growth Hormone
Hintergrund
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).