Cyclin A1 Antikörper (full length)

Produktnummer ABIN7878057

Der Maus Monoklonal anti-Cyclin A1 Antikörper wird verwendet zum Nachweis von Cyclin A1 in Proben von Human und Xenopus laevis. Er wurde validiert für WB.

Kurzübersicht für Cyclin A1 Antikörper (full length) (ABIN7878057)

Target: Cyclin A1 (CCNA1)

Reaktivität: Human, Xenopus laevis

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cyclin A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Güteklasse: Carrier-free

Klon: XLA1-3

Produktdetails anti-Cyclin A1 Antikörper

Bindungsspezifität: full length

Verwendungszweck: Cyclin A1 Antibody / CCNA1 (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: Recombinant full-length Xenopus laevis Cyclin A1 protein was used as the immunogen for the Cyclin A1 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Cyclin A1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Cyclin A1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Cyclin A1

Target: Cyclin A1 (CCNA1)

Andere Bezeichnung: Cyclin A1

Hintergrund: The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F, and retinoblastoma protein p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34. The antibody detects Xenopus cyclin A in blots. Cyclin A1 is the embryonic cyclin which is present in Xenopus eggs.

UniProt: P78396

Pathways: Apoptose, Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA