GJB1 Antikörper (AA 92-147)

Produktnummer ABIN7877153

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GJB1 in WB, FACS und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GJB1 Antikörper (AA 92-147) (ABIN7877153)

Target: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Produktdetails anti-GJB1 Antikörper

Bindungsspezifität: AA 92-147

Verwendungszweck: GJB1 Antibody / Gap junction beta-1 protein / Connexin 32

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids A92-A147) was used as the immunogen for the GJB1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the GJB1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the GJB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu GJB1

Target: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Andere Bezeichnung: GJB1

Hintergrund: Gap junction beta-1 protein (GJB1), also known as connexin 32 (Cx32) is a transmembrane protein that in humans is encoded by the GJB1 gene. This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

UniProt: P08034

Pathways: Cell-Cell Junction Organization