EPH Receptor A4 Antikörper (AA 875-904)

Produktnummer ABIN7877022

Der Kaninchen Polyklonal anti-EPH Receptor A4 Antikörper wird verwendet zum Nachweis von EPH Receptor A4 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für EPH Receptor A4 Antikörper (AA 875-904) (ABIN7877022)

Target: EPH Receptor A4 (EPHA4)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor A4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EPH Receptor A4 Antikörper

Bindungsspezifität: AA 875-904

Verwendungszweck: Ephrin type-A receptor 4 Antibody / EphA4

Aufreinigung: SAS precipitation

Immunogen: A portion of amino acids 875-904 from the human protein was used as the immunogen for the Ephrin type-A receptor 4 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Ephrin type-A receptor 4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot the Ephrin type-A receptor 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu EPH Receptor A4

Target: EPH Receptor A4 (EPHA4)

Andere Bezeichnung: Ephrin type-A receptor 4

Hintergrund: Ephrin type-A receptor 4, also known as Eph4A, is a member of the Eph receptor family. These receptors are involved in mediating cell-to-cell communication and are critical for various physiological processes such as tissue patterning, neuronal development, and immune response. One of the key functions of Eph4A is its role in axon guidance during neuronal development. Studies have shown that Eph4A is essential for establishing proper neuronal connections in the developing brain. Disruption of Eph4A signaling has been linked to various neurological disorders, highlighting the importance of this receptor in brain development. In addition to its role in neuronal development, Eph4A has also been implicated in cancer progression. Aberrant expression of Eph4A has been observed in various types of cancer, and targeting this receptor has shown promising results in inhibiting tumor growth and metastasis. Furthermore, Eph4A has been shown to play a role in immune response regulation. By modulating the activity of immune cells, Eph4A can influence the inflammatory response and contribute to the maintenance of immune homeostasis.

UniProt: P54764

Pathways: RTK Signalweg