Complement Factor H Antikörper (AA 751-780)

Produktnummer ABIN7876733

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Complement Factor H in WB, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Complement Factor H Antikörper (AA 751-780) (ABIN7876733)

Target: Complement Factor H (CFH)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Complement Factor H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Complement Factor H Antikörper

Bindungsspezifität: AA 751-780

Verwendungszweck: Complement factor H Antibody / CFH

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 751-780 from the human protein was used as the immunogen for the Complement factor H antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Complement factor H antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Complement factor H antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Complement Factor H

Target: Complement Factor H (CFH)

Andere Bezeichnung: Complement factor H

Hintergrund: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: P08603

Pathways: Komplementsystem, Cellular Response to Molecule of Bacterial Origin