GZMB Antikörper (AA 73-187)
Kurzübersicht für GZMB Antikörper (AA 73-187) (ABIN7876665)
Target
Alle GZMB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 73-187
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Verwendungszweck
- Granzyme B Antibody (azide and preservative free)
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- Amino acids 73-187 were used as the immunogen for the Granzyme B antibody.
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal dilution of the Granzyme B antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the Granzyme B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- GZMB (Granzyme B (GZMB))
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Andere Bezeichnung
- Granzyme B
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Hintergrund
- This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [UniProt]
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UniProt
- P10144
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose
Target
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