PFKL Antikörper (AA 669-699)

Produktnummer ABIN7876365

Der Kaninchen Polyklonal anti-PFKL Antikörper wird verwendet zum Nachweis von PFKL in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für PFKL Antikörper (AA 669-699) (ABIN7876365)

Target: PFKL (Phosphofructokinase, Liver (PFKL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFKL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PFKL Antikörper

Bindungsspezifität: AA 669-699

Verwendungszweck: PFKL Antibody / ATP-PFK / ATP-dependent 6-phosphofructokinase liver type

Immunogen: A portion of amino acids 669-699 from the human protein was used as the immunogen for the PFKL antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the PFKL antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PFKL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu PFKL

Target: PFKL (Phosphofructokinase, Liver (PFKL))

Andere Bezeichnung: PFKL

Hintergrund: The PFKL protein is an enzyme that catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate, a key step in the glycolytic pathway. It also plays a role in regulating glucose metabolism, which is crucial for maintaining healthy blood sugar levels. Dysregulation of the PFKL protein has been linked to metabolic disorders such as diabetes and obesity. While it is primarily found in the liver, where it helps regulate glucose production, it is also found in other tissues such as skeletal muscle and adipose tissue.

UniProt: P17858

Pathways: Negative Regulation of Hormone Secretion, Warburg Effekt