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PFKL Antikörper (Middle Region)

PFKL Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schaf, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782359
  • Target Alle PFKL Antikörper anzeigen
    PFKL (Phosphofructokinase, Liver (PFKL))
    Bindungsspezifität
    • 10
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schaf, Zebrafisch (Danio rerio)
    Wirt
    • 45
    • 5
    Kaninchen
    Klonalität
    • 46
    • 4
    Polyklonal
    Konjugat
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PFKL Antikörper ist unkonjugiert
    Applikation
    • 38
    • 23
    • 23
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Sequenz
    RTNVLGHLQQ GGAPTPFDRN YGTKLGVKAM LWLSEKLREV YRKGRVFANA
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 79%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PFKL. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PFKL
    Top Product
    Discover our top product PFKL Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 568 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

  • Target
    PFKL (Phosphofructokinase, Liver (PFKL))
    Andere Bezeichnung
    PFKL (PFKL Produkte)
    Synonyme
    PFK-B antikoerper, AA407869 antikoerper, phosphofructokinase, liver type antikoerper, phosphofructokinase, liver, B-type antikoerper, PFKL antikoerper, Pfkl antikoerper
    Hintergrund
    Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. PFK from muscle is a homotetramer of M subunit, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. PFKL represents the L subunit.
    Alias Symbols: DKFZp686G1648, DKFZp686L2097, FLJ30173, FLJ40909, PFK-B
    Protein Interaction Partner: KRTAP10-7, GTPBP3, PFKL, KRTAP5-9, FUS, STAU1, UBC, EGFR, RNF2, rev, ZC3HC1, PSMD9, FBXO6, YWHAQ, HDAC6, PRPF40A, TESK1, PFKM, MYD88, ITGA4, FN1, PCBP3, PRDX3, PFKP, APP, ATN1, RAD21, SNW1, TERF2, ATG101, TAF13, TAF10, DMWD, COPS6, KRTAP4-12,
    Protein Size: 568
    Molekulargewicht
    64 kDa
    Gen-ID
    5211
    NCBI Accession
    NM_002626
    UniProt
    P17858
    Pathways
    Negative Regulation of Hormone Secretion, Warburg Effekt
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