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PFKL Antikörper (Center)

PFKL Reaktivität: Human, Maus WB, IHC (p), IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856164
  • Target Alle PFKL Antikörper anzeigen
    PFKL (Phosphofructokinase, Liver (PFKL))
    Bindungsspezifität
    • 10
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 48
    • 24
    • 17
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 45
    • 5
    Kaninchen
    Klonalität
    • 46
    • 4
    Polyklonal
    Konjugat
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PFKL Antikörper ist unkonjugiert
    Applikation
    • 38
    • 23
    • 23
    • 6
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Rind (Kuh), Ratte (Rattus)
    Kreuzreaktivität (Details)
    Rat (95 %), Bovine (94 %)
    Produktmerkmale
    Rabbit Polyclonal antibody to PFKL (phosphofructokinase, liver)
    PFKL antibody [C1C3]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human PFKL. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Kommentare

    Positive Control: A431 , H1299 , HeLa , HepG2

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.8 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    PFKL (Phosphofructokinase, Liver (PFKL))
    Andere Bezeichnung
    PFKL (PFKL Produkte)
    Synonyme
    PFK-B antikoerper, AA407869 antikoerper, phosphofructokinase, liver type antikoerper, phosphofructokinase, liver, B-type antikoerper, PFKL antikoerper, Pfkl antikoerper
    Hintergrund
    Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. Separate genes encode a muscle subunit (M) and a liver subunit (L). PFK from muscle is a homotetramer of M subunits, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. The protein encoded by this gene represents the L subunit. Alternate splicing results in two transcript variants, one of which is a candidate for nonsense-mediated decay (NMD).

    Molekulargewicht
    85 kDa
    Gen-ID
    5211
    Pathways
    Negative Regulation of Hormone Secretion, Warburg Effekt
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