BIRC3 Antikörper (AA 59-88)

Produktnummer ABIN7875913

Der Kaninchen Polyklonal anti-BIRC3 Antikörper (ABIN7875913) detektiert spezifisch BIRC3 in WB, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für BIRC3 Antikörper (AA 59-88) (ABIN7875913)

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIRC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BIRC3 Antikörper

Bindungsspezifität: AA 59-88

Verwendungszweck: BIRC3 Antibody

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 59-88 from the human protein was used as the immunogen for the BIRC3 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the BIRC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the BIRC3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu BIRC3

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Andere Bezeichnung: BIRC3

Hintergrund: The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq].

UniProt: Q13489

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades