LEMD3 Antikörper (AA 535-852)

Produktnummer ABIN7875610

Der Kaninchen Polyklonal anti-LEMD3 Antikörper (ABIN7875610) detektiert spezifisch LEMD3 in WB, FACS und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für LEMD3 Antikörper (AA 535-852) (ABIN7875610)

Target: LEMD3 (LEM Domain Containing 3 (LEMD3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LEMD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Produktdetails anti-LEMD3 Antikörper

Bindungsspezifität: AA 535-852

Verwendungszweck: MAN1 Antibody / LEMD3

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids H535-H852) was used as the immunogen for the MAN1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MAN1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the MAN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu LEMD3

Target: LEMD3 (LEM Domain Containing 3 (LEMD3))

Andere Bezeichnung: MAN1

Hintergrund: LEM domain-containing protein 3 (LEMD3), also known as MAN1, is an integral protein in the inner nuclear membrane (INM) of the nuclear envelope. It is encoded by the LEMD3 gene and was first identified after it was isolated from the serum of a patient with a collagen vascular disease. This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.

UniProt: Q9Y2U8