LEMD3 Antikörper (AA 535-852) (HRP)

Produktnummer ABIN8005319

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LEMD3 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für LEMD3 Antikörper (AA 535-852) (HRP) (ABIN8005319)

Target: LEMD3 (LEM Domain Containing 3 (LEMD3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LEMD3 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-LEMD3 Antikörper (HRP)

Bindungsspezifität: AA 535-852

Verwendungszweck: Anti-LEMD3 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LEMD3 recombinant protein (Position: H535-H852).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu LEMD3

Target: LEMD3 (LEM Domain Containing 3 (LEMD3))

Andere Bezeichnung: LEMD3

Hintergrund:

Background: LEM domain-containing protein 3 (LEMD3), also known as MAN1, is an integral protein in the inner nuclear membrane (INM) of the nuclear envelope. It is encoded by the LEMD3 gene[5] and was first identified after it was isolated from the serum of a patient with a collagen vascular disease. This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.

Gene Full Name: LEM domain containing 3

Gen-ID: 23592

UniProt: Q9Y2U8