LEMD3 Antikörper (AA 535-852)

Produktnummer ABIN8005323

Der Kaninchen Polyklonal anti-LEMD3 Antikörper wird verwendet zum Nachweis von LEMD3 in Proben von Human. Er wurde validiert für WB, FACS und ELISA.

Kurzübersicht für LEMD3 Antikörper (AA 535-852) (ABIN8005323)

Target: LEMD3 (LEM Domain Containing 3 (LEMD3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LEMD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Güteklasse: Carrier-free

Produktdetails anti-LEMD3 Antikörper

Bindungsspezifität: AA 535-852

Verwendungszweck: Anti-LEMD3 Antibody

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Anti-LEMD3 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LEMD3 recombinant protein (Position: H535-H852).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu LEMD3

Target: LEMD3 (LEM Domain Containing 3 (LEMD3))

Andere Bezeichnung: LEMD3

Hintergrund:

Background: LEM domain-containing protein 3 (LEMD3), also known as MAN1, is an integral protein in the inner nuclear membrane (INM) of the nuclear envelope. It is encoded by the LEMD3 gene[5] and was first identified after it was isolated from the serum of a patient with a collagen vascular disease. This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.

Gene Full Name: LEM domain containing 3

Molekulargewicht: 120 kDa

Gen-ID: 23592

UniProt: Q9Y2U8