LEMD3 Antikörper (C-Term)

Produktnummer ABIN6991613

Produktdetails anti-LEMD3 Antikörper

Target: LEMD3 (LEM Domain Containing 3 (LEMD3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LEMD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: At least three isoforms of LEMD3 are known to exist, this antibody will detect all isoforms. LEMD3 antibody is predicted to not cross-react with LEMD1 and LEMD2

Aufreinigung: LEMD3 Antibody is affinity chromatography purified via peptide column.

Immunogen: LEMD3 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LEMD3. The immunogen is located within the last 50 amino acids of LEMD3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LEMD3 antibody can be used for detection of LEMD3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: LEMD3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: LEMD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu LEMD3

Target: LEMD3 (LEM Domain Containing 3 (LEMD3))

Andere Bezeichnung: LEMD3 (LEMD3 Produkte)

Synonyme: MAN1 antikoerper, AI316861 antikoerper, Man1 antikoerper, im:7158446 antikoerper, wu:fb34b12 antikoerper, si:dkey-6a5.6 antikoerper, RGD1561001 antikoerper, man1 antikoerper, sane antikoerper, xman1 antikoerper, lemd3 antikoerper, LEM domain containing 3 antikoerper, LEM domain containing 3 S homeolog antikoerper, LEMD3 antikoerper, Lemd3 antikoerper, lemd3 antikoerper, lemd3.S antikoerper

Hintergrund: LEMD3 Antibody: LEMD3 (LEM domain-containing 3) is a lem-domain containing protein, also known as MAN1, whose loss of function results in disorders characterized by osteopoikilosis, Buschke-Ollendorff syndrome, and melorheostosis. LEMD3 is an inner nuclear membrane protein that interacts with BMP and activin-TGF-beta receptor-activated Smads and antagonizes TGF-beta signaling in human cells.

Gen-ID: 23592

NCBI Accession: NP_055134

UniProt: Q9Y2U8