Rekombinanter SMAD4 Antikörper (AA 400-552)
Kurzübersicht für Rekombinanter SMAD4 Antikörper (AA 400-552) (ABIN7874726)
Target
Alle SMAD4 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 400-552
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Verwendungszweck
- SMAD4 Antibody (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A recombinant partial protein sequence (within amino acids 400-552) from the human protein was used as the immunogen for the SMAD4 antibody.
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Isotyp
- IgG, kappa
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Applikationshinweise
- Optimal dilution of the SMAD4 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Aliquot the SMAD4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SMAD4 (SMAD Family Member 4 (SMAD4))
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Andere Bezeichnung
- SMAD4
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Hintergrund
- SMAD4 is implicated as a tumor suppressor since it is inactivated in more than half of pancreatic carcinomas and to a lesser extent in a variety of other cancers. The lack of SMAD4 expression is present in approximately 80 % of cases of pancreatic adenocarcinoma, but rarely in endometrial (0 %), colorectal (0 %), ovarian (3 %), lung (0 %), breast (2 %) adenocarcinomas, and malignant melanoma (4 %). SMAD4is an important marker for confirming a diagnosis of pancreatic adenocarcinoma.
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UniProt
- Q13485
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Pathways
- Zellzyklus, Chromatin Binding, Autophagie
Target
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