Tyrosinase-Related Protein 1 Antikörper (AA 257-377)
Kurzübersicht für Tyrosinase-Related Protein 1 Antikörper (AA 257-377) (ABIN7872961)
Target
Alle Tyrosinase-Related Protein 1 (TYRP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 257-377
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Verwendungszweck
- Tyrosinase-Related Protein-1 Antibody / TRP1 / TYRP1 (azide and preservative free)
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- A recombinant human partial protein (amino acids 257-377) was used as the immunogen for this Tyrosinase-Related Protein-1 antibody.
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal dilution of the Tyrosinase-Related Protein-1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the Tyrosinase-Related Protein-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Tyrosinase-Related Protein 1 (TYRP1)
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Andere Bezeichnung
- Tyrosinase-Related Protein-1
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Hintergrund
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
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UniProt
- P17643
Target
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