RNASEH2A Antikörper (AA 25-299)

Produktnummer ABIN7872867

Der Kaninchen Polyklonal anti-RNASEH2A Antikörper wird verwendet zum Nachweis von RNASEH2A in Proben von Human. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für RNASEH2A Antikörper (AA 25-299) (ABIN7872867)

Target: RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNASEH2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-RNASEH2A Antikörper

Bindungsspezifität: AA 25-299

Verwendungszweck: RNase H2 subunit A Antibody / RNASEH2A

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R25-L299) was used as the immunogen for the RNase H2 subunit A antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the RNase H2 subunit A antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the RNase H2 subunit A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu RNASEH2A

Target: RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

Andere Bezeichnung: RNase H2 subunit A

Hintergrund: Ribonuclease H2 subunit A, also known as RNase H2 subunit A, is an enzyme that in humans is encoded by the RNASEH2A gene. The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.

UniProt: O75792