RNASEH2A Antikörper (AA 1-299)

Produktnummer ABIN7269981

Produktdetails anti-RNASEH2A Antikörper

Target: RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

Bindungsspezifität: AA 1-299

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNASEH2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: RNASEH2A Rabbit pAb

Sequenz: MDLSELERDN TGRCRLSSPV PAVCRKEPCV LGVDEAGRGP VLGPMVYAIC YCPLPRLADL EALKVADSKT LLESERERLF AKMEDTDFVG WALDVLSPNL ISTSMLGRVK YNLNSLSHDT ATGLIQYALD QGVNVTQVFV DTVGMPETYQ ARLQQSFPGI EVTVKAKADA LYPVVSAASI CAKVARDQAV KKWQFVEKLQ DLDTDYGSGY PNDPKTKAWL KEHVEPVFGF PQFVRFSWRT AQTILEKEAE DVIWEDSASE NQEGLRKITS YFLNEGSQAR PRSSHRYFLE RGLESATSL

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human RNASEH2A (NP_006388.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RNASEH2A

Target: RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))

Andere Bezeichnung: RNASEH2A (RNASEH2A Produkte)

Synonyme: 2400006P09Rik antikoerper, RNASEHI antikoerper, RNHIA antikoerper, RNHL antikoerper, zgc:56307 antikoerper, AGS4 antikoerper, JUNB antikoerper, ribonuclease H2 subunit A antikoerper, ribonuclease H2, large subunit antikoerper, ribonuclease H2, subunit A antikoerper, ribonuclease H2 subunit A L homeolog antikoerper, rnaseh2a antikoerper, RNASEH2A antikoerper, Rnaseh2a antikoerper, rnaseh2a.L antikoerper

Hintergrund: The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.,RNASEH2A,AGS4,JUNB,RNASEHI,RNHIA,RNHL,Epigenetics & Nuclear Signaling,RNASEH2A

Molekulargewicht: 33kDa

Gen-ID: 10535

UniProt: O75792