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MCL-1 Antikörper (pSer159, pThr163)

This anti-MCL-1 antibody (ABIN743738) is a Rabbit Polyclonal antibody detecting MCL-1 in WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro). Suitable for Human, Rat.
Produktnummer ABIN743738

Kurzübersicht für MCL-1 Antikörper (pSer159, pThr163) (ABIN743738)

Target

Alle MCL-1 (MCL1) Antikörper anzeigen
MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Reaktivität

  • 139
  • 62
  • 56
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Human, Ratte

Wirt

  • 132
  • 13
  • 1
  • 1
Kaninchen

Klonalität

  • 125
  • 24
Polyklonal

Konjugat

  • 78
  • 9
  • 9
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser MCL-1 Antikörper ist unkonjugiert

Applikation

  • 115
  • 58
  • 48
  • 44
  • 26
  • 25
  • 25
  • 18
  • 17
  • 13
  • 6
  • 5
  • 4
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 26
    • 16
    • 15
    • 11
    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer159, pThr163

    Spezifität

    These phosphorylation sites are homologous to Ser140 + Thr144 in Mouse and Ser139 + Thr143 in Rat.

    Kreuzreaktivität

    Human, Ratte

    Homologie

    Mouse,Dog,Cow,Horse

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from human Mcl 1 around the phosphorylation site of Ser159/Thr163

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Braig, Wiedmann, Liebl, Singer, Kubisch, Schreiner, Abhari, Wagner, Kazmaier, Fulda, Vollmar: "Pretubulysin: a new option for the treatment of metastatic cancer." in: Cell death & disease, Vol. 5, pp. e1001, (2014) (PubMed).

  • Target

    MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

    Andere Bezeichnung

    Mcl1 +

    Hintergrund

    Synonyms: TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, MCL1

    Background: Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

    Gen-ID

    4170

    UniProt

    Q07820

    Pathways

    MAPK Signalweg
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