CTLA4 Antikörper (AA 182-210)

Produktnummer ABIN7871464

Der Kaninchen Polyklonal anti-CTLA4 Antikörper (ABIN7871464) detektiert spezifisch CTLA4 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CTLA4 Antikörper (AA 182-210) (ABIN7871464)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTLA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CTLA4 Antikörper

Bindungsspezifität: AA 182-210

Verwendungszweck: CTLA4 Antibody / Cytotoxic T-lymphocyte protein 4 / CD152

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 182-210 from the human protein was used as the immunogen for this CTLA4 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the CTLA4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot the CTLA4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Andere Bezeichnung: CTLA4

Hintergrund: CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer.

UniProt: P16410

Pathways: Cancer Immune Checkpoints