Complement Factor H Antikörper (AA 136-447)

Produktnummer ABIN7870556

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Complement Factor H in WB, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Ratte und Maus.

Kurzübersicht für Complement Factor H Antikörper (AA 136-447) (ABIN7870556)

Target: Complement Factor H (CFH)

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Complement Factor H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Complement Factor H Antikörper

Bindungsspezifität: AA 136-447

Verwendungszweck: Cfh Antibody / Factor H

Aufreinigung: Affinity purified

Immunogen: Recombinant mouse protein (amino acids N136-T447) was used as the immunogen for the Cfh antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Cfh antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Cfh antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Complement Factor H

Target: Complement Factor H (CFH)

Andere Bezeichnung: Cfh

Hintergrund: Factor H is a member of the regulators of complement activation family and is a complement control protein. This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: P06909

Pathways: Komplementsystem, Cellular Response to Molecule of Bacterial Origin