MYD88 Antikörper (AA 136-164)

Produktnummer ABIN7870552

Der Kaninchen Polyklonal anti-MYD88 Antikörper (ABIN7870552) detektiert spezifisch MYD88 in WB, FACS und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MYD88 Antikörper (AA 136-164) (ABIN7870552)

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYD88 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MYD88 Antikörper

Bindungsspezifität: AA 136-164

Verwendungszweck: MyD88 Antibody

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 136-164 from the human protein was used as the immunogen for this MyD88 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the MyD88 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the MyD88 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu MYD88

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Andere Bezeichnung: MyD88

Hintergrund: Myeloid differentiation primary response protein MyD88 is an adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. It acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and increases IL-8 transcription. It may be involved in myeloid differentiation.

UniProt: Q99836

Pathways: NF-kappaB Signalweg, TLR Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades